Sophia Bush met Chad Michael Murray when the pair started filming "One Tree Hill" in Wilmington, North Carolina, in 2003. Murray proposed to his co-star in May 2004, and they wed less than a year later on April 16, 2005, in Santa Monica, California. However, the union wasn't meant to be, and just months later, the newlyweds split. 

According to Us Weekly, Bush initially filed for an annulment of the marriage, citing fraud as the reason, with rumors circulating that Murray had allegedly cheated on his wife with "House of Wax" co-star Paris Hilton. While the annulment was denied, the couple's divorce would subsequently be finalized in December 2006.

Following their divorce, they continued to work together on their hit show "One Tree Hill," and Bush has often spoken about her marriage to Murray. While appearing on "Watch What Happens Live" in January 2014, the actor said (as shared by Us Weekly), "We were two stupid kids who had no business being in a relationship in the first place." In June 2018, Bush appeared on Andy Cohen's SiriusXM show and suggested that she should never have married Murray, saying, "It was not a thing I actually really wanted to do, but you know, it's cool." She continued, "Ladies have to learn how to take up space in the way that men are taught they are entitled to."

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